Corey Keller, MD, PhD

Precision Neurotherapeutics: Biomarker-guided Neuromodulation for Psychiatry

Dr. Keller, MD, PhD, is an Associate Professor of Psychiatry and Behavioral Sciences at Stanford University. He received his MD and PhD in neuroscience from the Medical Scientist Training Program at Albert Einstein College of Medicine and completed psychiatry residency at Stanford focused on interventional psychiatry. The overarching goals of Dr. Keller’s Precision Neurotherapeutics Laboratory (precisionneuro.stanford.edu) is to improve brain stimulation treatment for neurological and psychiatric disorders. His lab focuses on understanding neural mechanisms of how brain stimulation techniques alter brain circuits in an effort to develop novel, personalized, and more effective interventions. His lab combines invasive and noninvasive brain stimulation coupled with electrophysiology techniques to answer these pressing questions.

Reading List

Chen NF, Hassan U, Ross JM, Forman L, Hartford JW, Gogulski J, Parmigiani S, Truong J, Keller CJ, Cline CC. Noninvasive profiling of input-output excitability curves in human prefrontal cortex. bioRxiv [Preprint]. 2025 Dec 4: 2025.09.26.678876. doi: 10.1101/2025.09.26.678876. PMID: 41040393; PMCID: PMC12485743.

Gogulski J, Cline CC, Ross JM, Truong J, Sarkar M, Parmigiani S, Keller CJ. Mapping cortical excitability in the human dorsolateral prefrontal cortex. Clin Neurophysiol. 2024 Aug; 164:138-148. doi: 10.1016/j.clinph.2024.05.008. Epub 2024 May 27. PMID: 38865780; PMCID: PMC11246810.

Keller CJ, Huang Y, Herrero JL, Fini ME, Du V, Lado FA, Honey CJ, Mehta AD. Induction and Quantification of Excitability Changes in Human Cortical Networks. J Neurosci. 2018 Jun 6;38(23):5384-5398. doi: 10.1523/JNEUROSCI.1088-17.2018. Epub 2024 May 21. PMID: 29875229; PMCID: PMC5990984.

Subramanian AK, Talbot A, Kim N, Parmigiani S, Cline CC, Solomon EA, Hartford JW, Huang Y, Mikulan E, Zauli FM, d’Orio P, Cardinale F, Mannini F, Pigorini A, Keller CJ. Scalp EEG predicts intracranial brain activity in humans. bioRxiv [Preprint]. 2025 Apr 7:2025.04.07.647612. doi: 10.1101/2025.04.07.647612. PMID: 40291696; PMCID: PMC12026988.

Wang, J.B., Hassan, U., Bruss, J.E., Oya, H., Uitermarkt, B.D., Trapp, N.T., Gander, P.E., Howard, M.A., Keller, C.J., & Boes, A.D. (2024). Effects of transcranial magnetic stimulation on the human brain recorded with intracranial electrocorticography. Molecular Psychiatry, 29(5), 1228-1240. https://doi.org/10.1038/s41380-024-02405-y